Module 5 questions - Species differences (Clinical challenge)
  1. Based on the information presented in this module does it appear that chloramphenicol can be given to cats in a way that is as effective, as safe and as practical as it is given to dogs?
  2. This quote appears in the USP monograph for Chloramphenicol: "Doses of 25 to 50 mg per kg of body weight every twelve hours have been recommended, and may be necessary for some infections, but could increase the risk of side effects". In terms of the plasma concentration vs time profile, why might 50 mg/kg be a more effective dose?
  3. Based on the same USP quote in question 2 and in terms of the plasma concentration vs time profile, why might 50 mg/kg be a more toxic dose?