Veterinary Pharmacokinetics (VM8314): | Home | Administration | Distribution | Elimination | Modeling | Models | Glossary |
"For nearly all veterinary patients and in nearly all cases, dosage is based on recommendations from references, trusted experts and/or drug labels. Pharmacokinetics are ONLY important to veterinarians if dosage modification improves clinical outcome (enhances efficacy, avoids intoxication)...
...and then pharmacokinetics are VERY important."-JRW
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![]() Your understanding of pharmacokinetics may improve if you visualize what's going on at a microscopic level. Shown here is a section of skeletal muscle. Visualize a blood vessel in this field (remember to make sure the tip of your needle really IS in among muscle cells and not in a vessel). Visualize what happens to those neatly arrayed fibers when you push a ball of pharmaceutical product in between them. ![]() No matter how they are administered, drugs (must) end up in the bloodstream. Nearly all pharmaceutical actions occur either in the interstitium (e.g. cell surface receptors) or inside of cells (e.g., intracytoplasmic receptors). Within each of these spaces the drug may be free in solution, bound to proteins or trapped as ions. |
Term | Definition |
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Dose |
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Dosage |
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Equillibrium |
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